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首页>> 名师风采 >> 中心研修导师>>
 
王月丹(基础医学院)
发布日期:2017-04-19 浏览次数: 5 字号:[ ]

  • 学历背景

医学博士(内科学)

 

  • 专业及科研方向

主要从事肿瘤免疫与血液免疫学研究,涉及癌/睾丸抗原和特异性CTL识别表位等研究方向。

 

  • 教学经历

主讲《医学免疫学》(国家精品资源共享课、国家级双语教学建设课程)、《高级免疫学》、《健康免疫学》、《临床免疫学》、《疾病免疫学》、《肿瘤免疫学》和《基础医学实验室设备与技术》等课程。

主编《医学免疫学》、《健康免疫学》、《医学免疫学与病原学实验教程》和《医学病原学与免疫学》等教材4部,获得发明专利授权2项。2005年获教育部新世纪优秀人才计划和北京市科技新星计划资助,2007年获教育部高等学校自然科学奖(一等奖),2010年获中华医学科技奖(二等奖),2011年获得国家自然科学奖(二等奖)。2010年获亚洲医学教育学会(AMEA)第四届学术大会最佳发言奖及2013年获香港大学医学教育论坛最佳发言等国际医学教育教学奖。

 

  • 教学感悟

医学教育的目标就是让那些立志从医的人胜任他们未来的职业岗位。

 

附:

  • 参与课题

1)教学课题

基于校际选修和暑期学校平台的非医学类本科生《健康免疫学》课程的建设与实践研究。(北京大学医学部教育教学研究课题)

2)科研课题

1、北京市自然科学基金面上项目,7162099,癌睾丸抗原特异性抗体及T细胞介导的过继免疫治疗多发性骨髓瘤的基础研究,2016/01-2018/1216万,在研,主持

2、国家自然科学基金面上项目,81172884,癌/睾丸抗原表位疫苗诱导的特异性T细胞及其在抗多发性骨髓瘤免疫中作用与机制研究,2012/01-2015/1260万元,已结题,主持

3、国家自然科学基金面上项目,30771995,癌-睾丸(CT)抗原在人多发性骨髓瘤中的表达及其多肽疫苗治疗多发性骨髓瘤的基础研究,2008/01-2010/1235万元,已结题,主持

4、国家自然科学基金面上项目,30671962,共刺激分子在新发传染病相关的全身炎症反应综合征中作用的基础研究,2007/01-2009/1228万元,已结题,主持

5、北京市科技新星计划,2005年,已结题

6、教育部新世纪优秀人才计划,2005年,50万元,已结题

7、国家自然科学基金青年科学基金项目,30300309HCA520分子在肿瘤细胞中的表达及其与肿瘤免疫应答的关系,2004/01-2006/1220万元,已结题,主持

8、国家自然科学基金专项基金项目,30340011SARS相关冠状病毒抗原肽疫苗的基础研究,2003/05-2005/0330万元,已结题,主持

 

  • 发表文章

教学文章:

1.王月丹; 白惠卿; 朱蕴兰; 张秀春。以竞赛激励促进医学免疫学双语教学的开展。中国高等医学教育。2007,(3):77

2. 王月丹, 白惠卿, 朱蕴兰, 张秀春, 徐兰。医学免疫学双语教学引入激励手段的探索。中华医学教育杂志。2007276):55-56

3. 王月丹,张燕,徐兰,张秀春,朱蕴兰。中美两校教师对以问题为基础学习教学中八个问题不同解决方法的比较与思考。中华医学教育杂志。2007275):97-98

4. 徐兰,王月丹,白惠卿。非医学院校本科生中开设健康免疫学课程的实践。中华医学教育杂志。20082843-44

5. 朱蕴兰; 马大龙; 徐晓军; 陈英玉; 鲁琰; 赵红珊; 赵振东; 袁志宏; 王月丹; 高晓明。RISEPBL教学模式在医学免疫学教学中的探索。中国高等医学教育。200611):93-94

6.教育杂志。徐兰,俞赤卉,初明,何嘉勰,陈雪,朱蕴兰,裴军,王月丹。翻转课堂和情景式教学在免疫学实验课中的设计与应用。中华医学2014, 34(6):898-901

 

科研文章:

(1)  Yue Dan Wang#, John De Vos#, Michel Jourdan, Guilhem Couderc, Zhao-Yang Lu, Jean-Fran?ois Rossi and Bernard Klein*,Cooperation between heparin-binding EGF-like growth factor and interleukin-6 in promoting the growth of human myeloma cells, Oncogene, 2002, 21(16):2584-92

(2)  Yue-Dan Wang#, Zong-Jiang Gu#, Jian-An Huang, Yi-Bei Zhu, Zhao-Hua Zhou, Wei Xie, Ying Xu, Yu-Hua Qiu, Xue-Guang Zhang*, gp130-linked signal transduction promotes the differentiation and maturation of dendritic cells, Int Immunol, 2002, 4(6):599-603

(3)  Yue-Dan Wang#, Wan-Yee Fion Sin#, Guo-Bing Xu#,Huang-Hua Yang, Tin-yau Wong, Xue-Wen Pang, Xiao-Yan He, Hua-Gang Zhang, Joice Na Lee Ng, Chak-Sum Samuel Cheng, Jing Ju, Li Meng, Rui-Feng Yang, Sik-To Lai, Zhi-Hong Guo, Yong Xie*, Wei-Feng Chen*,T-Cell Epitopes in Severe Acute Respiratory Syndrome (SARS) Coronavirus Spike Protein Elicit a Specific T-Cell Immune Response in Patients Who Recover from SARS, J Virol, 2004, 78(11): 5612–5618

(4)   Yue-Dan Wang#*, Yan Lia, Guo-Bin Xub, Xue-Yuan Donga, Xiao-Ang Yanga, Zhen-Ru Fengb, Chan Tiana, Wei Feng Chen*, Detection of antibodies against SARS-CoV in serum from SARS-infected donors with ELISA and Western blot, Clin Immunol, 2004, 113(2):145-50

(5)  Yue-Dan Wang#*, Wei Feng Chen*, Detecting specific cytotoxic T lymphocytes against SARS-coronavirus with DimerX HLA-A2:Ig fusion protein, Clin Immunol, 2004, 113(2):151-4

(6)  Kailin Yin*, Yanchen LiuMing Chu, Yuedan Wang*, TFDP3 Regulates Epithelial-Mesenchymal Transition in Breast Cancer, PLoS One, 2017, 12(1): e0170573.

(7)  Ming Chu*, Kailin Yin, Yujun Dong, Pingzhang Wang, Yun Xue, Peng Zhou, Yuqi Wang, Yuedan Wang*,TFDP3 confers chemoresistance in minimal residual disease within childhood T-cell acute lymphoblastic leukemia, Oncotarget, 2017, 8(1):1405-1415.

(8)  Ming Chu#*, Ming-bo Zhang, Yan-chen Liu, Jia-rui Kang, Zheng-yun Chu, Kai-lin Yin, Ling-yu Ding, Ran Ding, Rong-xin Xiao, Yi-nan Yin, Xiao-yan Liu, Yue-dan Wang*, Role of Berberine in the Treatment of Methicillin-Resistant Staphylococcus aureus Infections, Sci Rep, 2016, 6:24748

(9)  Ming Chu #* , Yue-Long Hou , Lan Xu, Zheng-Yun Chu, Ming-Bo Zhang, Yue-Dan Wang*, Evaluation of the Nano-TiO2 as a Novel Deswelling Material, Molecules, 2016, 21(1):57

(10)Ming Chu#, Lan Xu, Ming-bo Zhang, Zheng-yun Chu, Yue-dan Wang*, Role of Baicalin in Anti-Influenza Virus A as a Potent Inducer of IFN-Gamma, Biomed Res Int. 2015;2015:263630

(11)Ming Chu#, Jia-rui Kang, Wei Wang, Haichao Li, Jia-hui Feng, Zheng-yun Chu, Ming-bo Zhang, Lan Xu, Yue-dan Wang*, Evaluation of human epidermal growth factor receptor 2 in breast cancer with a novel specific aptamer, Cell Mol Immunol, 2015, doi: 10.1038/cmi.2015.31

(12)Ming Chu#*, Ran Ding, Zheng-yun Chu, Ming-bo Zhang, Xiao-yan Liu, Shao-hua Xie, Yan-jun Zhai, Yue-dan Wang*, Role of berberine in anti-bacterial as a high-affinity LPS antagonist binding to TLR4/MD-2 receptor, BMC Complement Altern Med. 2014, 14:89

(13)Peng Zhao#, Lijuan Zhang, Weijian Zhong, Xianping Ying, He Huang, Biyun Yao, Zhun Yuan, Juanling Fu, Yuedan Wang*, Zongcan Zhou*, Antigen-subtracted 2-DE/MS strategy, a novel proteomic analysis platform, Arch Toxicol, 2011, 85(1):35-41

(14)Jia-Zi Meng#, Yu-Jun Dong, He Huang, Shuang Li, Yi Zhong, Shu-Lin Liu, Yue-dan Wang*, Oral vaccination with attenuated Salmonella encoding T-cell epitopes from tumor antigen NY-ESO-1 induced specific CTL responses, Clin Vaccine Immunol, 2010, 17(6):889-94

(15)He Huang#,  Ye-Jun Wang,  Aaron P. White,  Jia-Zi Meng,  Gui-Rong Liu, Shu-Lin Liu*, Yue-dan Wang*, Salmonella expressing a T-cell epitope from Sendai virus are able to induce anti-infection immunity, J Med Microbiol, 2009, 58(Pt 9):1236-42

(16)Lijuan Zhang#, He Huang, Luyao Deng, Ming Chu, Lan Xu, Juanling Fu, Yunlan Zhu, Xiuchun Zhang, Shulin Liu, Zongcan Zhou, Yue-dan Wang*, TPX2 in malignantly transformed human bronchial epithelial cells by anti-benzo[a]pyrene-7,8-diol-9,10-epoxide, Toxicology, 2008, 252(1-3):49-55

(17)Rui Zhang#, Jie Huang, Fei Xie, Baojun Wang, Ming Chu, Yuedan Wang, Haichao Li, Wei Wang, Haixia Zhang, Wengang Wu, and Zhihong Li*, Microfluidic sterilization, Biomicrofluidics. 2014, 8(3): 034119

(18)Ananya Roy#, Jicheng Gong#, Duncan C. Thomas, Junfeng Zhang, Howard M. Kipen, David Q. Rich, Tong Zhu, Wei Huang, Min Hu, Guangfa Wang, Yuedan Wang, Ping Zhu, Shou-En Lu, Pamela Ohman-Strickland, Scott R. Dieh, Sandrah P. Eckel*,  The cardiopulmonary effects of ambient air pollution and mechanistic pathways: a comparative hierarchical pathway analysis, PLoS One, 2014, 9(12):e114913

(19)Jicheng Gong#, Tong Zhu, Howard Kipen, Guangfa Wang, Min Hu, Qingfeng Guo, Pamela Ohman-Strickland, Shou-En Lu, Yuedan Wang, Ping Zhu, David Q. Rich, Wei Huang, Junfeng Zhang*, Comparisons of ultrafine and fine particles in their associations with biomarkers reflecting physiological pathways, Environ Sci Technol, 2014, 48(9):5264-73

(20)Jianming Sang#, Hongtan Du, Wei Wang, Ming Chu, Yuedan Wang, Haichao Li, Haixia Alice Zhang, Wengang Wu, Zhihong Li*, Protein sensing by nanofluidic crystal and its signal enhancement, Biomicrofluidics, 2013, 7(2):24112

(21)CHU Wei-li#, CHU Ming, WANG Yue-dan, HU Yan, ZHAO Can, SU Li, XIONG Yan, YANG Tong-sheng, TAO Ying-hong , LI Hai-chao*, Effects of epithelial cell injury of the lower respiratory tract in the pathogenesis of allergic responses in a rat model, Chin Med J (Engl), 2013, 126(1):72-7

(22)Jicheng Gong#, Tong Zhu, Howard Kipen, Guangfa Wang, Min Hu, Pamela Ohman-Strickland, Shou-En Lu, Lin Zhang, Yuedan Wang, Ping Zhu, David Q. Rich, Scott R. Diehl, Wei Huang, and Junfeng (Jim) Zhang*, Malondialdehyde in exhaled breath condensate and urine as a biomarker of air pollution induced oxidative stress, J Expo Sci Environ Epidemiol, 2013, 23(3):322-7

(23)Wei Huang#, Guangfa Wang#, Shou-En Lu, Howard Kipen, Yuedan Wang, Min Hu, Weiwei Lin, David Rich, Pamela Ohman-Strickland, Scott R. Diehl, Ping Zhu, Jian Tong, Jicheng Gong, Tong Zhu, and Junfeng Zhang*Inflammatory and oxidative stress responses of healthy young adults to changes in air quality during the Beijing Olympics, Am J Respir Crit Care Med, 2012, 186(11):1150-9

(24)David Q. Rich#, Howard M. Kipen, MPH, Wei Huang, Guangfa Wang, Yuedan Wang, Ping Zhu, Pamela Ohman-Strickland, Min Hu, laire Philipp, Scott R. Diehl, Shou-En Lu, Jian Tong, Jicheng Gong, Duncan Thomas, Tong Zhu, and Junfeng (Jim) Zhang*, Association between changes in air pollution levels during the Beijing Olympics and biomarkers of inflammation and thrombosis in healthy young adults, JAMA, 2012, 307(19):2068-78

(25)Howard Kipen#, David Rich, Wei Huang, Tong Zhu, Guangfa Wang, Min Hu, Shou-en Lu, Pamela Ohman-Strickland, Ping Zhu, Yuedan Wang, and Jim (Junfeng) Zhang*, Measurement of inflammation and oxidative stress following drastic changes in air pollution during the Beijing Olympics: a panel study approach, Ann N Y Acad Sci, 2010, 1203:160-7

(26)Suping Li#, Quanwei Shi, Guanglei Liu, Weilin Zhang, Zhicheng Wang, Yuedan Wang, Kesheng Dai*, Mechanism of platelet functional changes and effects of anti-platelet agents on in vivo hemostasis under different gravity conditions, J Appl Physiol (1985), 2010, 108(5):1241-9

(27)Kesheng Dai#*, Yuedan Wang, Rong Yan, Quanwei Shi, Zhicheng Wang, Yanhong Yuan, Hong Cheng, Suping Li, Yubo Fan, Fengyuan Zhuang*, Effects of microgravity and hypergravity on platelet functions, Thromb Haemost, 2009,101(5):902-10.

(28)Guo-Dong Li#, Xi Zhang, Rong Li, Yue-Dan Wang, Yan-Li Wang, Ke-Jun Han, Xiao-Ping Qian, Cheng-Gang Yang, Ping Liu, Qun Wei, Wei-Feng Chen, Jun Zhang, Yu Zhang*, CHP2 activates the calcineurin/nuclear factor of activated T cells signaling pathway and enhances the oncogenic potential of HEK293 cells, J Biol Chem. 2008, 283(47):32660-8

(29)Xiao Ang Yang#, Xue Yuan Dong, Huan Qiao, Yue Dan Wang, Ji Run Peng, Yan Li, Xue Wen Pang, Chan Tian, Wei Feng Chen*, Immunohistochemical analysis of the expression of FATE/BJ-HCC-2 antigen in normal and malignant tissues, Lab Invest, 2005, 85(2):205-13.

(30)B Li#, Y Wang, J Chen, H Wu, W Chen*, Identification of a new HLA-A*0201-restricted CD8+ T cell epitope from hepatocellular carcinoma-associated antigen HCA587, Clin Exp Immunol, 2005, 140(2):310-9

(31)Xue-Yuan Dong#, Xiao-Ang Yang, Yue-Dan Wang, Wei-Feng Chen*, Zinc-finger protein ZNF165 is a novel cancer-testis antigen capable of eliciting antibody response in hepatocellular carcinoma patients, Br J Cancer, 2004, 91(8):1566-70

(32)Xue-Yuan Dong#, Xue-Wen Pang, Song-Tao Yu, Yan-Rong Su, Hong-Chen Wang, Yan-Hui Yin, Yue-Dan Wang, Wei-Feng Chen*, Identification of genes differentially expressed in human hepatocellular carcinoma by a modified suppression subtractive hybridization method, Int J Cancer, 2004, 112(2):239-48.

(33)Xiao Ang Yang#, Xue Yuan Dong, Yan Li, Yue Dan Wang, Wei Feng Chen*, Purification and refolding of a novel cancer/testis antigen BJ-HCC-2 expressed in the inclusion bodies of Escherichia coli, Protein Expr Purif, 2004, 33(2):332-8.

(34)R C-F Chan, X-W Pang, Y-D Wang, W-F Chen*, Y Xie*, Transduction of dendritic cells with recombinant adenovirus encoding HCA661 activates autologous cytotoxic T lymphocytes to target hepatoma cells, Br J Cancer, 2004, 90(8):1636-43

(35)Zhao-Hua Zhou#, Jiang-Fang Wang, Yue-Dan Wang, Yu-Hua Qiu, Jiang-Zhong Pan, Wei Xie, Ling-Yu Jiang, Bernard Klein, Xue-Guang Zhang*, An agonist anti-human CD40 monoclonal antibody that induces dendritic cell formation and maturation and inhibits proliferation of a myeloma cell line, Hybridoma, 1999, 18(6):471-8

 




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